Do myelodysplastic syndrome always present with immunologic abnormalities?

Any insult to our bodies may lead to immunologic reactions. Up to 30% of patients shows evidence of some autoimmune phenomen. These may range from laboratory test abnormalities, such as positive rheumatoid factor, to syndrome with prominent cutaneous vasculitis, arthritis and fever. Other manifestation are xerositis, polymyalgia rheumatica, Raynaud's phenomen, and Sjogren syndrome. These syndrome generally respond to steroid therapy